Dr. Nick Ghazarian, DO · Los Angeles

Regenerative spine care, with precision.

Board-certified orthopedic surgeon and fellowship-trained spine surgeon. Nonsurgical first, minimally invasive when it matters.

5.0 ★★★★★ 94 Google reviews

Our approach

Most spine and joint conditions improve without surgery. We begin with the least invasive path, and recommend an operation only when it will clearly serve you.

Coordinated conservative care

Physical therapists, nutritionists, chiropractors and acupuncturists, working from one plan.

Regenerative medicine

PRP, A2M and bone marrow concentrate, prepared from your own blood or marrow.

Minimally invasive surgery

State-of-the-art procedures for when an operation is the right answer.

Regenerative medicine

Repair, guided by your own biology.

For many patients, regenerative treatments relieve pain and restore function while avoiding or delaying surgery.

Platelet-rich plasma

Your own blood, in office

Platelet-rich plasma

Platelets are concentrated from a small sample of your blood and placed precisely, under image guidance, to support healing in tendons, ligaments, joints and the spine.

Alpha-2-Macroglobulin (A2M)

Your own blood, protein-based

Alpha-2-Macroglobulin (A2M)

A naturally occurring protein concentrated from your blood. A2M binds and inhibits enzymes that break down cartilage, and is often considered for joint and disc-related pain.

Bone marrow concentrate (BMC)

Your own bone marrow

Bone marrow concentrate (BMC)

A small bone marrow sample, typically drawn from the back of the pelvis, is concentrated to deliver cellular and growth-factor components to degenerative joints and spine structures.

Conditions we evaluate

When regenerative therapies may be considered.

Regenerative injections are most often considered for chronic musculoskeletal conditions that haven't fully responded to conservative care. Whether any therapy is appropriate is determined on a case-by-case basis after a clinical evaluation.

Degenerative disc disease

Targeted injections to support disc and facet joint healing.

Knee & hip osteoarthritis

Reduce inflammation and slow cartilage degeneration.

Tendon injuries

Tennis elbow, rotator cuff, Achilles tendinopathy, plantar fasciitis.

Chronic low back pain

Sacroiliac and lumbar facet joint pain that hasn't responded to therapy.

Sports & overuse injuries

Accelerate return-to-play after muscle, ligament, or joint strain.

Post-surgical recovery

Adjunctive therapy to enhance healing after orthopedic procedures

Regenerative treatment

What to expect, step by step.

  1. Consultation & diagnosis

    Dr. Ghazarian reviews your history, imaging, and exam findings to discuss whether a regenerative option may be appropriate — or whether a different approach is a better fit.

  2. Sample collection

    A small blood sample (PRP / A2M) or bone marrow sample (BMC) is collected. Most visits take roughly 30–60 minutes depending on the therapy.

  3. Concentration

    The sample is processed in a medical-grade system to concentrate the platelets, proteins, or cellular components used for the injection.

  4. Image-guided injection

    Using ultrasound or fluoroscopic guidance when indicated, the concentrate is delivered to the targeted spine or joint structure.

  5. Recovery & follow-up

    Most patients resume normal activity within 24–48 hours. Any biologic response develops gradually over the following weeks; results vary by individual.

Surgery

When surgery is the answer.

If surgical intervention is inevitable, we offer state-of-the-art, minimally invasive procedures to treat a multitude of spinal disorders.

Minimally invasive spine surgery

Smaller incisions and less disruption to surrounding muscle, for decompression and stabilization of the spine.

Cervical disc replacement

A motion-preserving option for selected neck conditions, replacing a damaged disc rather than fusing the level.

Conditions we treat

Neck pain Back pain Nerve compression Disc herniation Spinal stenosis Joint pain Tendon injuries
All procedures

Our team

A small team. Undivided attention.

One goal: identify the source of pain, explain the options clearly, and build a plan that fits your condition, goals and lifestyle.

Nick Ghazarian, DO

Founder · Orthopedic & spine surgeon

Nick Ghazarian, DO

Board-certified orthopedic surgeon and fellowship-trained spine surgeon, and Director of Minimally Invasive Spine Surgery at Dignity Health Glendale Memorial Hospital. He lectures nationally and internationally on minimally invasive techniques and strategies to avoid unnecessary surgery.

NASS AAOS SMISS
Emin Keshishyan, PA-C

Board-certified physician assistant

Emin Keshishyan, PA-C

Many years in orthopedic and spine care, working closely with Dr. Ghazarian. Emin is involved throughout your care: evaluations and follow-up visits, injections, casting and splinting, perioperative education, postoperative management and rehabilitation planning.

Concierge

Concierge care, on request.

For patients who value their time and privacy: a single point of contact and priority access to Dr. Ghazarian's schedule.

Dedicated patient coordinator

One person manages your scheduling, imaging, insurance and follow-up, from the first call through full recovery.

Same- and next-day appointments

Priority scheduling for when pain can't wait, with time set aside to answer every question.

Patient reviews

5.0

★★★★★

94 Google reviews
Dr. Ghazarian was very kind and explained everything in so much detail. He answered all of our questions and spent a lot of time with us. The surgery went well and the scar is so small.
Julia G.
Super passionate, super humble and I can tell he loves what he does, which is helping people.
Artin A.
Dr. Ghazarian took the time to address all my concerns and was thorough and compassionate. Overall, I'd highly recommend him, you'll be in good hands.
Krishil G.
The staff is as pleasant on the phone as they are in person… Dr. Ghazarian especially. He takes the time to LISTEN and make sure you understand.
Jennifer P.
Beyond the operating room.

Community & humanitarian work

Beyond the operating room.

Dr. Ghazarian is Co-Founder and Medical Director of the Armenian Mesopotamian Christian Care Initiative (AMCCI), a nonprofit supporting medical outreach, humanitarian assistance and medical education, including volunteer work in Armenia.

Our humanitarian work
This field is for validation purposes and should be left unchanged.
Please use this form for general information purposes only. DO NOT send personal health information through this form. Specific patient care must be addressed during your appointment.
The phone numbers collected for the SMS consent will never be shared with third parties or affiliates for marketing purposes under any circumstances.
Call Us Appointments

Accessibility Tools

Increase TextIncrease Text
Decrease TextDecrease Text
GrayscaleGrayscale
Invert Colors
Readable FontReadable Font
Reset